Fine-needle aspiration cytology of amyloid associated with nonneoplastic and malignant lesions

1998 ◽  
Vol 18 (4) ◽  
pp. 270-275 ◽  
Author(s):  
Bradford E. Halliday ◽  
Jan F. Silverman ◽  
James L. Finley
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Malignant Lesions ◽  
Needle Aspiration Cytology

COMPUTED TOMOGRAPHY CORRELATION OF THORACIC LESIONS WITH TRANSTHORACIC FINE NEEDLE ASPIRATION CYTOLOGY AND BIOPSY

2019 ◽  
Vol 2 (2) ◽  
Author(s):  
Rajneesh Madhok ◽  
Ashish Gupta ◽  
Lalit Singh ◽  
Tanu Agarwal
Keyword(s):  
Fine Needle Aspiration ◽  
Predictive Value ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Ct Guided ◽  
Fine Needle ◽  
Malignant Lesions ◽  
Needle Aspiration Cytology ◽  
Adequate Tissue

INTRODUCTION: The study is an attempt to evaluate the sensitivity, specificity, positive predictive value, negative predictive value, p Value and complications of CT guided thoracic interventions fine needle aspiration cytology and core biopsy which are used for diagnosing benign and malignant thoracic lesions. MATERIAL AND METHODS: Study included 102 Patients (87 males and 15 females) with age group ranged from 15 to 87 years.A total of 143 CT guided interventions (84 FNAC’s and 59 core biopsies) were performed in 102 patients. The tissue obtained was sent to the laboratory for histopathological and cytological analysis for a final diagnosis which would contribute to patient management. RESULTS: All( 59) core biopsies were successful in procuring adequate tissue for histopathological analysis and the yield of core biopsies was 100% .However out of 84 FNAC’s only 4 were unsuccessful in procuring adequate tissue with a failure rate of 4.8%. Post procedural biopsy complications were only three (2.1%) which were small pneumothorax. There were 75 malignant lesions and 23 benign lesions based on cytology and histopathology (4 were excluded due to inadequate sample). There was good agreement between benign and malignant lesions diagnosed on CT and that diagnosed by pathology. The most common benign and malignant lesions were granulomatous lesion and squamous cell carcinoma. CONCLUSION: Percutaneous CT guided interventions like core biopsy and fine needle aspirations cytology are simple minimal invasive procedures with good patient acceptance and low morbidity and almost negligible mortality. CT guided interventions should be performed early for diagnosis of thoracic lesions.

Role of Fine Needle Aspiration Cytology in Hepatic Lesions

2021 ◽  
Vol 15 (8) ◽  
pp. 1894-1895
Author(s):  
Hira Taimoor
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Ultrasound Guided ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Malignant Lesions ◽  
Needle Aspiration Cytology ◽  
Hepatic Lesions

Background: Fine needle aspiration cytology (FNAC) is used as a diagnostic tool for masses or lumps. Ultrasound-guided FNAC is usually used for the diagnosis of hepatic lesions. Aim: To analyze the role of ultrasound-guided fine needle aspiration cytology in the differentiation of hepatic lesions in benign and malignant lesions. Methods: During one year total 83 cases were selected and their FNAC was performed. Cases were analyzed after routine staining. Cell blocks were prepared where blood stained material was aspirated. Results: Mean age of the patients was 52±7.8 years and M: F of 1.3:1. 8 cases (9.64%) had low cellularity smear, 18 cases (21.69%) were of benign origin and 57 cases (68.67%) revealed malignant lesions, eight cases (9.64%) were of primary origin and 51 cases (59.03%) were of secondary origin. Conclusion: Ultrasound-guided FNAC is a useful and accurate method and can be used for diagnosis of different kinds of hepatic lesions. Keywords: Hepatic lesions, Ultrasound-guided fine needle aspiration cytology, cell blocks,

Fine-needle aspiration cytology of submandibular gland lesions

1995 ◽  
Vol 109 (9) ◽  
pp. 853-858 ◽  
Author(s):  
Timo Atula ◽  
Reidar Grénman ◽  
Pekka Laippala ◽  
Pekka-Juhani Klemi
Keyword(s):  
Submandibular Gland ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Neoplastic Lesions ◽  
Malignant Lesions ◽  
Needle Aspiration Cytology

AbstractThe usefulness of fine-needle aspiration cytology (FNAC) in the diagnosis and treatment of submandibular gland lesions is not well known. The 210 FNACs taken from submandibular gland lesions at Turku University Central Hospital between 1984 and 1991 were reviewed. Of these FNACs, 78 samples from primary lesions were confirmed histologically. Within this subset 10 FNACs were taken from benign neoplasms, all of which were correctly classified (sensitivity 100 per cent; specificity 88 percent). Only four of the 14 FNACs from malignant lesions were cytologically considered malignant (sensitivity 29 per cent). On the other hand, four FNACs raised a false suspicion of malignancy (specificity 6 per cent). Out of 54 FNACs from non-neoplastic lesions 43 were correct (sensitivity 80 per cent; specificity 63 per cent). There were 104 patients (123 FNACs), who had not been operated on: the follow-up of these patients shows that in this subset of FNACs there were no false malignant but probably one false benign finding (1 per cent). We conclude that FNAC can offer valuable information about the type of the submandibular gland lesion, but the decision of operative and other treatment should not be based solely on the result of FNAC.

scholarly journals Analysis of mediastinal lesions: a study of 27 cases

1970 ◽  
Vol 1 (2) ◽  
pp. 114-117 ◽  
Author(s):  
S Karki ◽  
S Chalise
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumor ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Cell Tumor ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Malignant Lesions ◽  
Needle Aspiration Cytology

Background: Mediastinum is a site of non-neoplastic and neoplastic lesions, many of which present as mediastinal masses. The purpose of this study was to study our institutional experience of mediastinal lesions on fine needle aspiration cytology or biopsy. Materials and Methods: This was a retrospective study of 27 patients, who had undergone fine needle aspiration cytology or biopsy for mediastinal lesions from April 2009 to November 2010 in the Department of Pathology, Institute of Medicine, Tribhuwan University Teaching Hospital. All details of the patients pertinent clinical history was obtained from case record file in the department. Results: Out of 27 cases, 18 cases (66.6%) were benign and 7 (26%) were malignant and 2 (7.4%) were inconclusive. Among the malignant lesions, primary tumors constituted 71.5% of cases while metastases were 28.5%. Most of the lesions were seen in the anterior compartment followed by the posterior compartment. Age range was 4 months to 70 years with a mean age of 35.5 years. Thymoma (8 cases) was the commonest lesion seen in mediastinum followed by germ cell tumor and neurogenic tumor. Conclusion: Benign mediastinal lesions are more common than malignant lesions with thymoma being the most commonly diagnosed mediastinal lesion. Keywords: Mediastinum; Germ cell tumor; Thymoma; Non Hodgkin Lymphoma DOI: http://dx.doi.org/10.3126/jpn.v1i2.5404 JPN 2011; 1(2): 114-117

scholarly journals Utility of fine needle aspiration cytology in head and neck lesions and its correlation with histopathology- a study in tertiary care hospital

2020 ◽  
Vol 10 (2) ◽  
pp. 1733-1741
Author(s):  
Sushma Thapa ◽  
Arnab Ghosh ◽  
Dilasma Ghartmagar ◽  
Sudeep Regmi ◽  
OP Talwar
Keyword(s):  
Head And Neck ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Tertiary Care ◽  
Needle Aspiration ◽  
Care Hospital ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Malignant Lesions ◽  
Needle Aspiration Cytology

Background: Fine Needle Aspiration Cytology has rapidly gained acceptance due to the easy accessibility of target sites and minimally invasive nature. It is a very simple, quick, cost-effective method of sampling alternative to the time consuming complicated and invasive excision biopsy. The study aimed to access the utility of fine needle aspiration cytology in the diagnosis of various head and neck lesions and also to establish the diagnostic accuracy between the cytological and histopathological diagnosis. Materials and Methods: A retrospective observational study of 380 cases of FNACs on head and neck swellings performed in various age groups in the Department of Pathology of a tertiary care hospital from January 2018 to December 2019.  Results: Out of 380 patients, the maximum number of cases were seen in the thyroid (40.8%), followed by lymph nodes (39.5%), skin, soft tissue, miscellaneous (10.8%) and salivary glands (8.9%). Benign and non-neoplastic cases outnumbered (88.1%) the malignant (10.8%) cases. Histopathological follow-up was available in 28 (7.4%) cases among which 25 (89.3%) cases were consistent with the cytodiagnosis. The sensitivity, specificity, and diagnostic accuracy were evaluated to be 80%, 94.4%, and 89.3% respectively. Conclusions: The majority of the cases of head and neck swellings were seen in the thyroid followed by lymph nodes, skin, soft tissue, miscellaneous, and salivary glands. In thyroid, colloid goiter and papillary carcinoma were the commonest benign and malignant lesions respectively. In the lymph node, reactive lymphadenitis, and metastatic squamous cell carcinoma were the commonest benign and malignant lesions respectively.

scholarly journals A study of correlation of pre-operative fine needle aspiration cytology and ultrasonography with post-operative histopathology in thyroid swellings

2020 ◽  
Vol 7 (5) ◽  
pp. 1456
Author(s):  
Rajkumar Parameshwar Narayanakar ◽  
Darshan Saligrama Govinda Shetty
Keyword(s):  
Sensitivity And Specificity ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
High Sensitivity ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Malignant Lesions ◽  
Needle Aspiration Cytology

Background:Diseases of the thyroid gland can be due to inflammatory and neoplastic causes. Many diagnostic tests like ultrasound, thyroid nuclear scan and fine needle aspiration cytology (FNAC) are available for their evaluation. Histopathologically, they can be adenomas, colloid nodules, cysts, infectious nodules, lymphocytic or granulomatous nodules, congenital abnormalities or hyperplasia, or various types of malignancy. It is therefore crucial to have a clear diagnostic approach to ensure patients are managed appropriately and are not over or under-treated. Present study was done to evaluate FNAC and ultrasonography (USG) as a diagnostic method in thyroid swellings and to plan surgery accordingly.Methods: A prospective observational study was conducted among 60 adult patients undergoing thyroid surgery at Victoria and Bowring and Lady Curzon Hospital. They were investigated with FNAC and USG of thyroid, and were subjected to surgery and subsequent histopathological examination. The histopathological examination reports were correlated with the findings of FNAC and USG in order to evaluate their findings by statistical methods.Results:The sensitivity and specificity of FNAC was 87.5% and 98% respectively. All malignant lesions on FNAC were confirmed by histopathology indicating its excellence. Therefore FNAC helps in planning the correct management and avoids second surgery. And the sensitivity and specificity of USG was 75% and 86% respectively. Therefore combination of both FNAC and ultrasonography will improve the diagnostic accuracy to higher level and helps in better management. Conclusions:FNAC has high sensitivity and specificity, so it is closest to ideal test. However, a combination of both FNAC and ultrasound will give desirable results and so that we can avoid mismanagement.

Influence of the Histopathological Features of the Lesion on the Diagnostic Yield of Fine-Needle Aspiration Cytology of Pancreatic Solid Lesions

2018 ◽  
Vol 62 (4) ◽  
pp. 259-264
Author(s):  
M. Jesús Fernández Aceñero ◽  
M. Vázquez ◽  
J.M. Esteban ◽  
Guillermo García Diego ◽  
Cristina Díaz del Arco
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Tertiary Hospital ◽  
Cytologic Diagnosis ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Number Of Patients ◽  
Malignant Lesions ◽  
Needle Aspiration Cytology

Objective: The rate of pancreatic lesions has increased in recent decades due to the widespread use of advanced imaging techniques. Nowadays, a significant proportion of cases are incidentally discovered in asymptomatic patients and cytology is an important tool for the diagnosis and multidisciplinary management of these cases. Study Design: In this study we retrospectively review the experience with pancreatic fine-needle aspiration cytology in the last 17 years at a single large tertiary hospital in Madrid, Spain. Results: Our results indicate that more than 60% of pancreatic malignant lesions are cytologically confirmed before surgery and 30% of the patients are asymptomatic. Despite this, we have noted that the total number of malignant lesions surgically resected in our hospital has basically remained unchanged over the years, because incidental diagnosis is not always synonymous with resectability and a substantial number of patients are already metastatic at the time of diagnosis. Our series also shows an increase in the number of neuroendocrine tumors, which now represent almost 20% of all cytological diagnoses at our hospital. The sensitivity in our series is 70% and the false negative rate remains 30%, despite sample quality control by experienced cytologists and standardized technical conditions. Fibrosis and necrosis are the 2 features of the primary tumor that significantly and negatively influence the accuracy of cytologic diagnosis. Conclusion: We herein report our experience with cytologic diagnosis of pancreatic lesions in a single tertiary hospital. Our results confirm that cytology is a safe, reliable, and important tool for pancreatic lesion diagnosis and management.

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